Acetazolamide responsive episodic ataxia treated with methazolamide: a case report
Acetazolamide-responsive ataxia is a rare episodic ataxia (EA) disorder characterized by paroxysmal cerebellar ataxia. Many of the symptoms with EA can be treated with the carbonic anhydrase inhibitor acetazolamide. EA is a family of channelopathies each with its own unique mutation. We report a case of EA treated with methlazolamide in a 37 year old man who experienced dysguesia with acetazolamide. Methazolamide has higher rates of diffusion into the tissue and a longer half-life compared with acetazolamide. It should be considered for episodic ataxia.
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