Rare Manifestation Of Churg-Strauss Syndrome: Coronary Artery Vasospasm Complicated By Myocardial Infarction
Keywords:churg-strauss syndrome, myocardial infarction, coronary vasospasm
Churg-Strauss syndrome (CSS) is a rare multisystemic disorder of unknown origin and cardiac involvement is one of the most serious manifestations of the disease.
Vasospastic angina and myocardial infarction are unusual clinical manifestations of Churg-Strauss syndrome (CSS).
We report a case of Churg-Strauss syndrome coexistent with myocardial infarction due to coronary vasospasm. A 25-year-old man with bronchial asthma and allergic rhinitis was admitted to our hospital because of acute respiratory distress and atypical chest pain. Angiography showed diffuse coronary artery spasm with healthy arteries. Myocardial infarction due to coronary vasospasm was diagnosed. In addition, marked eosinophilia, eosinophilic pneumonitis, chronic sinusitis, nasal endoscopy was performed objectifying nasal polyposis. The histological analysis of the polyposis biopsy revealed extravascular eosinophilic infiltrates. Combination therapy of glucocorticoids and cyclophosphamide was initiated.
Rigamonti F, De Benedetti E, Letovanec I, Rosset A, Chizzolini C. Cardiac involvement in Churg-Strauss syndrome mimicking acute coronary syndrome. SwissMed Wkly 2012;142:w13543.
Gianpiero D'Amico , Luca Nai Fovino1, Umberto Cucchini, Luisa Cacciavillani, Sabino Iliceto, Paolo Buja. Non-culprit coronary vasospasm in a woman affected by Churgâ€“Strauss syndrome presenting with ST-elevation myocardial infarction. International Journal of Cardiology 177 (2014) e10â€“e12
Tanaka M,Mise N, Kurita N, et al. A case of Churgâ€“Strauss Syndrome with necrotizing crescentic glomerulonephritis accompanied by acute coronary syndrome due to vasospasm. Am J Kidney Dis 2010;56(2):e5â€“9.
Wagner AD, Meyer GP, Rihl M, Rathmann A, Wittkop U, Zeidler H, et al. Acute coronary syndrome associated with Churg-Strauss syndrome. Vasc Health Risk Manag 2007;3:775-9.
Fabio Rigamontia, Edoardo De Benedettib, Igor Letovanecc, Antoine Rossetd, Carlo Chizzolinie. Cardiac involvement in Churg-Strauss syndrome mimicking acute coronary syndrome. Published 19 March 2012, doi:10.4414/smw.2012.13543
Masi AT, Hunder GG, Lie JT, et al. The American College of Rheumatology 1990 criteria for the classification of Churg-Strauss syndrome (allergic granulomatosis and angiitis). Arthritis Rheum 33: 1094-1100, 1990.
14. Setoguchi M, Okishige K, Sugiyama K, et al. Sudden cardiac death associated with Churg-Strauss syndrome. Circ J. 2009;73(12):2355-2359.
Hae Chang Jeong, Kye Hun Kim, et al . Cardiac Involvement of Churg-Strauss Syndrome as a Reversible Cause of Dilated Cardiomyopathy.J Cardiovasc Ultrasound 2015;23(1):40-43
G Sauvetre, J. Fares , et al . usefuless of magnetic resonance imaging in churgstrauss syndrome related cardiac involvement. A case series of three patients and literature review. La revue de mÃ©decine interne 31 (2010) 600-605.
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