Rare Manifestation Of Churg-Strauss Syndrome: Coronary Artery Vasospasm Complicated By Myocardial Infarction

Authors

  • radi fatima zohra department of cardiology B, university hospital of rabat
  • hara loubna department of cardiology B, university hospital of rabat
  • el ouazzani amine department of cardiology B, university hospital of rabat
  • berroho ouassima department of cardiology B, university hospital of rabat
  • doghmi nawal department of cardiology B, university hospital of rabat
  • zarzur jamila department of cardiology B, university hospital of rabat
  • cherti mohamed department of cardiology B, university hospital of rabat
  • tazi mzaalek zoubida department of internal medicine, university hospital of rabat
  • sefiani sanae department of pathological anatomy, university hospital of rabat
  • lahma jawad department of otolaryngology, university hospital of rabat
  • el ayoubi ali department of otolaryngology, university hospital of rabat

DOI:

https://doi.org/10.3823/2248

Keywords:

churg-strauss syndrome, myocardial infarction, coronary vasospasm

Abstract

Churg-Strauss syndrome (CSS) is a rare multisystemic disorder of unknown origin and cardiac involvement is one of the most serious manifestations of the disease.

Vasospastic angina and myocardial infarction are unusual clinical manifestations of Churg-Strauss syndrome (CSS).

We report a case of Churg-Strauss syndrome coexistent with myocardial infarction due to coronary vasospasm. A 25-year-old man with bronchial asthma and allergic rhinitis was admitted to our hospital because of acute respiratory distress and atypical chest pain. Angiography showed diffuse coronary artery spasm with healthy arteries. Myocardial infarction due to coronary vasospasm was diagnosed. In addition, marked eosinophilia, eosinophilic pneumonitis, chronic sinusitis, nasal endoscopy was performed objectifying nasal polyposis. The histological analysis of the polyposis biopsy revealed extravascular eosinophilic infiltrates. Combination therapy of glucocorticoids and cyclophosphamide was initiated.

References

Rigamonti F, De Benedetti E, Letovanec I, Rosset A, Chizzolini C. Cardiac involvement in Churg-Strauss syndrome mimicking acute coronary syndrome. SwissMed Wkly 2012;142:w13543.

Gianpiero D'Amico , Luca Nai Fovino1, Umberto Cucchini, Luisa Cacciavillani, Sabino Iliceto, Paolo Buja. Non-culprit coronary vasospasm in a woman affected by Churg–Strauss syndrome presenting with ST-elevation myocardial infarction. International Journal of Cardiology 177 (2014) e10–e12

Tanaka M,Mise N, Kurita N, et al. A case of Churg–Strauss Syndrome with necrotizing crescentic glomerulonephritis accompanied by acute coronary syndrome due to vasospasm. Am J Kidney Dis 2010;56(2):e5–9.

Wagner AD, Meyer GP, Rihl M, Rathmann A, Wittkop U, Zeidler H, et al. Acute coronary syndrome associated with Churg-Strauss syndrome. Vasc Health Risk Manag 2007;3:775-9.

Fabio Rigamontia, Edoardo De Benedettib, Igor Letovanecc, Antoine Rossetd, Carlo Chizzolinie. Cardiac involvement in Churg-Strauss syndrome mimicking acute coronary syndrome. Published 19 March 2012, doi:10.4414/smw.2012.13543

Masi AT, Hunder GG, Lie JT, et al. The American College of Rheumatology 1990 criteria for the classification of Churg-Strauss syndrome (allergic granulomatosis and angiitis). Arthritis Rheum 33: 1094-1100, 1990.

14. Setoguchi M, Okishige K, Sugiyama K, et al. Sudden cardiac death associated with Churg-Strauss syndrome. Circ J. 2009;73(12):2355-2359.

Hae Chang Jeong, Kye Hun Kim, et al . Cardiac Involvement of Churg-Strauss Syndrome as a Reversible Cause of Dilated Cardiomyopathy.J Cardiovasc Ultrasound 2015;23(1):40-43

G Sauvetre, J. Fares , et al . usefuless of magnetic resonance imaging in churgstrauss syndrome related cardiac involvement. A case series of three patients and literature review. La revue de médecine interne 31 (2010) 600-605.

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Published

2017-01-25

Issue

Section

Cardiology