Vitamin D Status of Behcetâ€™s Patients. Analysis of Correlation with Activity and Severity of the Disease as well as with the Quality of Life of Patients
Keywords:Behcet Syndrome, Vitamin D Defiiency, Disease Activity, Disease Severity, Patientsâ€™ Quality Of Life
Background: Vitamin D defiiency may increase the risk of variousÂ autoimmune diseases. But few studies focused on its role in BehcetÂ syndrome.
Objectives: The aims of our study were to assess the vitamin DÂ status of Behcet patients and to analyze the correlation of this statusÂ with the activity and the severity of the disease as well as the qualityÂ of life of patients.
Patients and methods: The vitamin D status was assessed in 40 patients with Behcet syndrome (average age: 37.5 years, sex ratio:Â 1.85) in comparison with 40 healthy control subjects matched by age,Â sex and by season of assessment. A correlation study was realizedÂ between vit D levels and duration of disease progression, its activity,Â its severity as well as the quality of life of patients.
Results: The average rate of vit D was 14.64 ng/ml (3-44.29 ng/ml). 94.6% of them had hypovitaminose D. Vit D defiiency has beenÂ attested in 35.1% and insuffiiency in 59.5% of the cases. There wasÂ no signifiant difference between rates of vit D in Behcet patients andÂ those of healthy controls. There was also no signifiant associationÂ between vit D levels in Behcet patients and duration of disease progression, activity and severity as well as their quality of life.
Conclusion: we made the evidence of hypovitaminose D in BehcetÂ patients. Even if its role in the determination of Behcet syndrome isÂ not obvious, this track remains to be explored.
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