The Lipodystrophy Syndrome as a Risk Marker for Cardiovascular Disease in Patients with HIV/AIDS Treated with HAART

Authors

  • Valdelias Xavier Pereira
  • Luiz Carlos de Abreu Faculdade de Medicina do ABC. Departamento de Saúde da Coletividade. Disciplina de Metodologia Científica.
  • Vitor Engrácia Valenti
  • Rodrigo Daminello Raimundo
  • Mariliza Henrique Silva
  • Fernando Rocha Oliveira
  • Renata Salatini
  • Adriano Luiz Roque
  • Marcia de Toledo Blake
  • Marcia de Toledo Blake
  • Erick Silva Dias
  • Celso Ferreira Filho
  • Vivian Finotti
  • Celso Ferreira

DOI:

https://doi.org/10.3823/1677

Keywords:

HIV, Lipodystrophy syndrome, cardiovascular disease, AIDS

Abstract

Introduction: The classic risk factors for cardiovascular disease in healthy individuals are well known, however, it lacks in the literature the mechanisms that predicts cardiovascular disease in the population living with HIV-AIDS treated with HAART and presenting syndrome lipodystrophy. We aimed to investigate the risk of cardiovascular disease in HIV-AIDS patients treated with HAART and lipodystrophy syndrome. Methods: A search was performed in Medline, SciELO, Lilacs and Cochrane using the intersection between the keywords: "cardiovascular disease", "HIV", "AIDS", "HAART" and "lipodystrophy syndrome". Results: The selected studies demonstrated that metabolic disorders such as hyperlipidemia, central adipose hypertrophy and peripheral lipoatrophy, besides the metabolic syndrome and lipodystrophy are maker clear risks of developing cardiovascular disease in these individuals. Conclusion: The metabolic alterations in HIV-AIDS treated with HAART and presenting lipodystrophy syndrome may potentiate the development of cardiovascular diseases.

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Published

2015-04-20

Issue

Vol. 8 (2015)

Section

Cardiology

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