Case Study: Pseudomonas aeruginosa Blood Stream Infection showing Derepressed  AmpC β-lactamase Hyper-producing Mutants

Authors

  • Jamal Wadi
  • Muhannad Yacoub
  • Nahil  Halloub
  • Rula Mohammad Rashed

Keywords:

Pseudomonas aeruginosa, Derepressed AmpC β-lactamase, Septic shock, chromosomally mediated, D-phenomena.

Abstract

Here we describe a middle aged-woman who had septic shock caused by a strain of Pseudomonas aeruginosa carrying derepressed AmpC hyper-producing genes. This was brought into view when the strain located in pipracillin/tazobactam area was exposed on agar plate to imipenem by diffusion causing “D-phenomenaâ€. Clinicians and microbiologists have to be aware of this phenomenon for a better choice of antimicrobials in treating their patients.

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Published

2013-02-25

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Section

Articles