Antimicrobial susceptibility and virulence factors of Enterococci colonizing intestinal tract of infants

Authors

  • Nazha A. Alnasra Pathology-Microbiology, Faculty of Medicine, The University of Jordan, Amman, Jordan
  • Eman F Badran Departments of Pediatrics , Jordan University Hospital, Amman, Jordan
  • Naheel Dajan Pathology-Microbiology, Faculty of Medicine, The University of Jordan, Amman, Jordan
  • Asem A. Shehabi The Jordan University, Amman

DOI:

https://doi.org/10.3823/783

Keywords:

Fecal enterococci, Infants, Antimicrobial resistance, Virulence factors

Abstract

Aim: This study investigated distribution of enterococci colonizing intestinal tract of infants and  has determined their putative virulence factors and antimicrobial susceptibility patterns. 

Methods:  A total of 82/186 (44.1%) fecal enterococcal isolates were recovered from infants. All enterococci isolates were identified either E. faecalis or E. faecium  using culture and PCR.

Results: A significant higher intestinal colonization of  enterococci was detected among non-hospitalized compared to hospitalized patients with a percentage of  (72 % vs. 28%), respectively . E.faecalis was the predominant species in both groups (75.6%). It had also significantly higher virulence factors genes than E. faecium ,while  E. faecium had higher rates of antimicrobial resistance than E.faecalis. 

Conclusion: This study shows significantly higher rate of intestinal colonization of  E.faecalis than E. faecium  of hospitalized and non-hospitalized infants, and  E.faecalis carried significantly higher potential virulence genes than E. faecium.

 

Key word: Fecal enterococci, Infants, Antimicrobial resistance, Virulence factors

Short title: Fecal ente

Author Biographies

Nazha A. Alnasra, Pathology-Microbiology, Faculty of Medicine, The University of Jordan, Amman, Jordan

Pathology-Microbiology,MSc.

Eman F Badran, Departments of Pediatrics , Jordan University Hospital, Amman, Jordan

Departments of  Pediatrics, Prof.

Naheel Dajan, Pathology-Microbiology, Faculty of Medicine, The University of Jordan, Amman, Jordan

Pathology-Microbiology,MSc.

Asem A. Shehabi, The Jordan University, Amman

Deapaertment of Pathology-Microbiology, Prof.

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2016-05-03

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