The The effect of High Dose of Vitamin D3 on the Prognosis of Patients with Multiple Sclerosis
Introduction. Multiple Sclerosis is a chronic inflammatory neurodegenerative disease of large magnitude in the world.
Method and Goal. To analyze primary studies associating high dose of vitamin D with the prognosis of patients with multiple sclerosis.
Results. 9 studies were selected, including 1022 participants. 630 of them were randomized to vitamin D3 supplementation in high dose, 171 in low-dose and 221 receiving placebo.
Conclusion. There is evidence that high dose of Vitamin D3 provide immunomodulatory effects in patients with Multiple Sclerosis, showing improvement in the patients' prognosis.
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