Metabolic Syndrome: Individual Components in Women who Had Preeclampsia History and Normal Risk Pregnancy
DOI:
https://doi.org/10.3823/1995Keywords:
Metabolic Syndrome X, Pre-eclampsia, Insulinresistence, Cardiovascular Diseases.Abstract
Introduction: Preeclampsia is a serious complication of pregnancy and childbirth that can contribute to the late onset of cardiovascular risk factors, among which the metabolic syndrome. Objective: identifying the prevalence of metabolic syndrome and its individual components in women who had preeclampsia and normal risk of pregnancy, evaluated five years after delivery. Method: analytical and descriptive, cross-sectional study with data collection conducted from March to December 2011 in a maternity hospital school, Natal-RN-Brazil. The sample included 70 women who had previous preeclampsia and 75 with normal pregnancy, selected by simple random probability sampling method. Results: It appeared as a cardiovascular risk factor, with statistical significance for metabolic syndrome p = 0.042, but also the fasting glucose levels p = 0.030, HDL cholesterol p = 0.049, systolic and diastolic pressure p <0.001. Conclusion: Therefore, preeclampsia appears as a potential risk factor for metabolic syndrome. Hence as long-term cardiovascular risk factor.
References
Stekkinger E, Scholten R, van der Vlugt M, van Dijk A, Janssen M, SpaandermanM. Metabolic syndrome and the risk for recurrent pre-eclampsia: a retrospective cohort study.BJOG. 2013 Jul; 120(8):979-86.
Montenegro CAB, Rezende Filho J. Rezende obstetrÃcia fundamental. Rio de Janeiro: Guanabara Koogan, 2014.
Mosca L, Benjamin EJ, Berra K, Bezanson JL, Dolor RJ, LIoyd-Jones DM, et al. Effectiveness-based guidelines for the prevention of cardiovascular disease in women-2011. Update: a guideline from the American Heart Association. Circulation. 2011;123:1243-62.
George E. M. Granger, JP. Endothelin: key mediator ofhypertension in preeclampsia. Am J Hypertens. 2011 Sep;24(9): 964–9.
Bilhartz TD, Bilhartz PA, Bilhartz TN, Bilhartz RD. Making use of a natural stress test: Pregnancy and cardiovascularrisk. J. Womens Health. 2011;20:695–701.
Kandaraki E, Christakou C, Diamanti-Kandarakis E. Metabolic syndrome and polycystic ovary syndrome... and vice versa. Arq Bras Endocrinol Metabol. 2009 Mar;53(2):227-37.
Mabry, R. M. et al. Gender differences in prevalence of the metabolic syndrome in Gulf Cooperation Council Countries: a systematic review. Diabet Med. 2010 May;27(5):593- 7.
Wang, W. et al. Epidemiological Investigation of Metabolic Syndrome and Analysis of Relevant Factors in North-eastern China. J Int Med Res. 2010 Jan/Feb;38(1):150-9.
Jover A, Corbella E, Muñoz A, Millán J, Pintó X, Mangas A, et al. Prevalencia Del sÃndrome metabólico y de sus componentes en pacientes con sÃndrome coronario agudo. Rev Esp Cardiol. 2011;64 (7):579-86.
Lu J, Zhao YY, Qiao J, Zhang HJ, Ge L, Wei Y. A follow-up study of women with a history of severe preeclampsia: relatioship between metabolic syndrome and preeclampsia. Chin Med J. 2011;124(5):775-79.
Mottillo S1, Filion KB, Genest J, Joseph L, Pilote L, Poirier P, et al. The metabolic syndrome and cardiovascular risk: a systematic review and meta-analysis. J Am Col lCardiol. 2010 Sep 28;56(14):1113-32.
Leão LSCS, Barros EG, Koifman RJ. Prevalência de SÃndrome Metabólica em Adultos Referenciados para Ambulatório de Nutrição no Rio de Janeiro, Brasil. Rev Bras Cardiol. 2010 Mar/Apr; 23(2): 93-100.
Smith GN, Pudwell J, Walker M, Wen SW. Ten-year, thirty-year, and lifetime cardiovascular disease risk estimates following a pregnancy complicated by preeclampsia. J. Obstet. Gynaecol. Can. 2012;34(9): 830-5.
Azevedo MF, Costa EC, Oliveira AIN, Silva IBO, Marinho JCDB, Rodrigues JAMR, et al. NÃveis pressóricos elevados em mulheres com sÃndrome dos ovários policÃsticos: prevalência e fatores de risco associados. Rev Bras Ginecol Obstet. 2011;33(1):31-6.
Brasil. Sociedade Brasileira de Cardiologia. Sociedade Brasileira de Hipertensão. Sociedade Brasileira de Nefrologia. VI Diretrizes Brasileiras de Hipertensão. Arq Bras Cardiol 2010; 95(supl.1):1-51.
World Health Organization (WHO). Physical status: the use and interpretation ofanthropometry. Report of a WHO Expert Committee.WHO Tech Rep Ser. 1995;854: 1-452.
International Diabetes Federation (IDF). The IDF consensus worldwide definition of the metabolic syndrome. International Diabetes Federation (IDF) [Internet]. 2006 [cited 2013 Jun 10]; [about. 24 p.]. Available from: http://www.idf.org/webdata/docs/Metac_syndrome_def.pdf.
Brasil. Diretrizes e normas regulamentadoras de pesquisa em seres humanos. Resolução nº 466 de 12 de dezembro de 2012. BrasÃlia (DF): Ministério da Saúde; 2012.
Niu JM , Lei Q , Lü LJ , Wen JY , Lin XH , Duan DM , et. al. Evaluation of the diagnostic criteria of gestational metabolic syndrome and analysis of the risk factors. Zhonghua Fu Chan Ke Za Zhi 2013 Feb;48 (2):92-7.
Yang JJ, Lee SA, Choi JY, Song M, Han S, Yoon HS, et. al. Subsequent risk of metabolic syndrome in women with a history of preeclampsia: data from the Health Examinees Study. J Epidemiol. 2015 Mar;25(4):281-8.
Smith GN, Pudwell J, Walker M, Wen SW. Risk estimation of metabolic syndrome atone and three years after a pregnancy complicated by preeclampsia. J Obstet Gynaecol Can.2012 Sep;34(9):836-41.
Pierin MG, Marroni SN, Taveira LAF, Bensenor IJM. Controle da hipertensão arterial e fatores associados na atenção primária em Unidades Básicas de Saúde localizadas na Região Oeste da cidade de São Paulo.Ciência & Saúde Coletiva [Online], 2011;16(Supl.1):1389-1400.
Kim JY, Mun HS, Lee BK, Yoon SB, Choi EY, Min PK, et. al. Impact of metabolic syndrome and its individual components on the presence and severity of angiographic coronary artery disease. Yonsei Med J. 2010;51:676–682.
Allen R, Rogozinska E, Sivarajasingam P, Khan KS, Thangaratinam S. Effect of diet- and lifestyle-based metabolic risk-modifying interventions on preeclampsia: a meta-analysis. Acta Obstet Gynecol Scand. 2014 Oct; 93(10): 973-85.
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