Cardiovascular Risk in HIV/AIDS and Lipodystrophy Syndrome Patients

Authors

  • Valdelias Xavier Pereira
  • Fernando Rocha Oliveira
  • Luiz Carlos de Abreu Faculdade de Medicina do ABC. Departamento de Saúde da Coletividade. Disciplina de Metodologia Científica.
  • Mariliza Henrique da Silva
  • Celso Ferreira Filho
  • Fernando Adami
  • Francisco Winter do Santos Figueiredo
  • Laércio da Silva Paiva
  • Renata Macedo Martins Pimentel
  • Vitor Engracia Valenti
  • Adriano Luis Roque
  • Rubens Wajnsztejn
  • Tatiana Dias de Carvalho
  • Karina Viviani de Oliveira Pessoa
  • Celso Ferreira

DOI:

https://doi.org/10.3823/1813

Keywords:

HIV, AIDS, cardiovascular disease, highly active antiretroviral therapy

Abstract

Background:The treatment of people living with AIDS, known a highly active antiretroviral therapy (HAART), has increased considerably, and the disease has therefore acquired chronic features. Several changes have been observed, especially in cardiovascular disease risk. Objective: To assess cardiovascular risk in HIV/AIDS patients treated with HAART and compare this with Lipodystrophy Syndrome (LS) carriers. Methods: This is a descriptive cross-sectional study. 192 patients were recruited from a lipodystrophy outpatient centre, using Framingham risk scores. Results: After criteria inclusion/exclusion, the final sample consisted of 81 patients divided into two groups (HIV/AIDS - without lipodystrophy and HIV/LS - with lipodystrophy). The mean age of HIV/AIDS was 46.5 years, and of the HIV/LS patients was 52 years. In accordance with Framingham scores the cardiovascular risk in HIV/AIDS was 46.59% and 14.29% in HIV/LS. Conclusion: The risk of cardiovascular disease over 10 years is significantly higher in patients with lipodystrophy syndrome.

References

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Published

2015-10-06

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Section

Cardiovascular Biology

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