Vaginal Yeasts and the Antifungal Action of Red Propolis Extract

Authors

  • Kévia Katiúcia Santos Bezerra Federal University of Campina Grande.
  • Maria do Carmo Andrade Duarte de Farias Federal University of Campina Grande.
  • Patrício Borges Maracajá Federal University of Campina Grande.
  • Alfredina dos Santos Araújo Federal University of Campina Grande.
  • Rosilene Agra da Silva Federal University of Campina Grande.
  • Antônio Fernandes Filho Federal University of Campina Grande.
  • Anne Milane Formiga Bezerra Nurse in a Mobile Emergency Service, MSU, Sousa, PB, Brazil.
  • Aucelia Cristina Soares Belchior Teacher of Faculty Santa Maria, Cajazeiras, Paraíba, Brazil; and Faculties Integrated of Patos, PB, Brazil.
  • Francisco Alírio da Silva Federal University of Campina Grande.
  • Wilma Katia Trigueiro Bezerra Nurse in a Mobile Emergency Service, MSU, Sousa, PB, Brazil.
  • Cláudia Sarmento Gadelha Federal University of Campina Grande.
  • Joyce Carolle Bezerra Cavalcante Federal University of Campina Grande.

DOI:

https://doi.org/10.3823/1753

Keywords:

Propolis, Candida, Vulvovaginitis, Products with antimicrobial action.

Abstract

Introduction: Vulvovaginitis is an inflammatory process that affects the vulva, vagina and cervix, most of the times of infectious cause. Vulvovaginal candidiasis is the second most frequent cause in Brazil, in Europe ranks first. Candida spp can be found in the vagina up to 20% of asymptomatic women.

Objective: Understanding the occurrence of vaginal yeasts and evaluating the antifungal action of a red propolis extract.

Method: This is a clinical study in vitro with vaginal secretion samples collected from 197 patients treated at the Health Center Frei Damiao in Patos-PB, Brazil. The species were identified using a chromogenic medium CHROMagar Candida®. At the end, the antifungal activity of the red propolis extract in four different concentrations was observed: 25%, 50%, 75% and 100%, by test disc Agar diffusion. The study was approved by the Research Ethics Committee of the Federal University of Campina Grande, CAAE 35203614.8.0000.5575.

Results: Of the samples analyzed other species identified by the medium used were the most prevalent corresponding to 59.8%, followed by C. albicans, with 21.7%. The antifungal activity was observed in 81.25% of the tested samples. According to the average and standard deviation of the inhibition zone of the four concentrations, the one that presented the smallest variation was the concentration at 50%, followed by concentration to 75%.

Conclusions: The results of this research showed that there was antifungal action of red propolis extract, since occurred inhibition in 81.25% of the analyzed samples. However did not show clearance regarding this action, since positivity tendency was not growing by increasing or decreasing the concentration of propolis extract.

Author Biographies

Kévia Katiúcia Santos Bezerra, Federal University of Campina Grande.

Academic Unit of Life Sciences, Teacher training center,

Maria do Carmo Andrade Duarte de Farias, Federal University of Campina Grande.

Academic Unit of Life Sciences, Teacher training center,

Patrício Borges Maracajá, Federal University of Campina Grande.

Graduate-degree in Agroindustrial Systems, Pombal, PB, Brazil.

Alfredina dos Santos Araújo, Federal University of Campina Grande.

Graduate-degree in Agroindustrial Systems, Pombal, PB, Brazil.

Rosilene Agra da Silva, Federal University of Campina Grande.

Graduate-degree in Agroindustrial Systems, Pombal, PB, Brazil.

Antônio Fernandes Filho, Federal University of Campina Grande.

Academic Unit of Nursing, Teacher training center,

Anne Milane Formiga Bezerra, Nurse in a Mobile Emergency Service, MSU, Sousa, PB, Brazil.

Nurse in a Mobile Emergency Service, MSU, Sousa, PB, Brazil.

Aucelia Cristina Soares Belchior, Teacher of Faculty Santa Maria, Cajazeiras, Paraíba, Brazil; and Faculties Integrated of Patos, PB, Brazil.

Teacher of Faculty Santa Maria, Cajazeiras, Paraíba, Brazil; and Faculties Integrated of Patos, PB, Brazil.

Francisco Alírio da Silva, Federal University of Campina Grande.

Academic Unit of Life Sciences, Teacher training center,

Wilma Katia Trigueiro Bezerra, Nurse in a Mobile Emergency Service, MSU, Sousa, PB, Brazil.

Nurse in a Mobile Emergency Service, MSU, Sousa, PB, Brazil.

Cláudia Sarmento Gadelha, Federal University of Campina Grande.

Academic Unit of Life Sciences, Cajazeiras, Paraíba, Brasil.

Joyce Carolle Bezerra Cavalcante, Federal University of Campina Grande.

Student of Medicine, Academic Unit of Life Sciences, Cajazeiras, Paraíba, Brasil.

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